MICRONUCLEUS ASSAY IN UROTHELIAL CELLS IS A DIAGNOSTIC INDICATOR IN CARCINOMA CERVIX
نویسندگان
چکیده
منابع مشابه
The Micronucleus Test in Urothelial Cells and Uterine Smears of Cervix Cancer Patients: A Comparison
Cytogenetic damage was assessed using the (MN) test in urothelial cells and cervix smears of local cervix cancer patients since the genetic end-point screening for micronuclei provides a measure of both, chromosome breakage and loss. The MN data were grouped for stage-types of cancer, age-groups, age-atmarriage, parity levels and socio-economic status. A comparison of the results obtained from ...
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Background & Objective: Micronucleus assay of buccal mucosa cells is a simple bio- monitoring method for diagnosing the genetic damages of toxic agents. The aim was to study the genotox...
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Background and objective:Cytogenetic damage in exfoliated buccal epithelial cells due to environmental and occupational exposure is often monitored by micronucleus (MN) assay using liquid based cytology (LBC) preparations. This study was performed to evaluate MN in exfoliated buccal epithelial cells of building construction workers using LBC preparations. <strong...
متن کاملOptimizing urothelial cell preparation for the human urinary micronucleus assay.
Biological monitoring of early genotoxic effects in urothelial cells using the urinary micronucleus (MNu) assay is promising for early detection of cancer, such as bladder carcinoma. But many problems are encountered, the major being the poorly differential staining of cells, particularly in women having an important amount of squamous cells. We have optimized the protocol and obtained a differ...
متن کاملMicronucleus assay- an early diagnostic tool to assess genotoxic changes in tobacco and related habits
Objective: Micronuclei are induced in cells by a variety of substances, like UV radiation, infrared rays, X-radiations, and chemicals. Among them tobacco- specific nitrosamines have been reported to be potent mutagenic agents which are thought to be responsible for the induction of chromosomal aberrations resulting in production of micronuclei. The main aim of our study is to compare MN frequen...
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ژورنال
عنوان ژورنال: Journal of Evolution of Medical and Dental Sciences
سال: 2015
ISSN: 2278-4748,2278-4802
DOI: 10.14260/jemds/2015/751